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Radiosensitization of Prostate Cancer by Priming the Wild-type p53-Dependent Cellular Senescence Pathway

A dramatic stage-migration in diagnosis of prostate cancer has led to earlier detection of clinically localized carcinoma and an increased use of radiation therapy. The p53 protein responds to irradiation-induced DNA damage by removing critically damaged cells from the proliferative pool. This revie...

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Библиографические подробности
Главные авторы: Lehmann, Brian D., McCubrey, James A., Terrian, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889025/
https://ncbi.nlm.nih.gov/pubmed/18059157
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