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Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status
Sirtuins (SIRT) belonging to the NAD+ dependent histone deacetylase III class of enzymes have emerged as master regulators of metabolism and longevity. However, their role in prevention of organismal aging and cellular senescence still remains controversial. In the present study, we now report upreg...
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Publicado no: | Cell Cycle |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4968900/ https://ncbi.nlm.nih.gov/pubmed/27229617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1189041 |
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