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Increased expression of SIRT2 is a novel marker of cellular senescence and is dependent on wild type p53 status

Sirtuins (SIRT) belonging to the NAD+ dependent histone deacetylase III class of enzymes have emerged as master regulators of metabolism and longevity. However, their role in prevention of organismal aging and cellular senescence still remains controversial. In the present study, we now report upreg...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Anwar, Tarique, Khosla, Sanjeev, Ramakrishna, Gayatri
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968900/
https://ncbi.nlm.nih.gov/pubmed/27229617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1189041
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