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Cellular senescence: ex vivo p53-dependent asymmetric cell kinetics

Although senescence is a defining property of euploid mammalian cells, its physiologic basis remains obscure. Previously, cell kinetics properties of normal tissue cells have not been considered in models for senescence. We now provide evidence that senescence is in fact the natural consequence of n...

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Detalhes bibliográficos
Main Authors: Rambhatla, Lakshmi, Bohn, Shirley A, Stadler, Patrizia B, Boyd, Jonathan T, Coss, Ronald A, Sherley, James L
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC79675/
https://ncbi.nlm.nih.gov/pubmed/12488624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724301000079
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