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Radiosensitization of Prostate Cancer by Priming the Wild-type p53-Dependent Cellular Senescence Pathway
A dramatic stage-migration in diagnosis of prostate cancer has led to earlier detection of clinically localized carcinoma and an increased use of radiation therapy. The p53 protein responds to irradiation-induced DNA damage by removing critically damaged cells from the proliferative pool. This revie...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2007
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889025/ https://ncbi.nlm.nih.gov/pubmed/18059157 |
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