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ANTISENSE-MDM2 SENSITIZES LNCaP PROSTATE CANCER CELLS TO ANDROGEN DEPRIVATION, RADIATION, AND THE COMBINATION IN VIVO
PURPOSE: To test the effects of antisense (AS)-MDM2 alone and with androgen deprivation (AD), radiotherapy (RT), and AD + RT on wild-type LNCaP cells in an orthotopic in vivo model. METHODS: Androgen-sensitive LNCaP cells were grown in the prostates of nude mice. Magnetic resonance imaging–based tum...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763094/ https://ncbi.nlm.nih.gov/pubmed/17637390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2007.03.047 |
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