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Antisense MDM2 Enhances the Response of Androgen Insensitive Human Prostate Cancer Cells to Androgen Deprivation In Vitro and In Vivo
BACKGROUND: Antisense MDM2 oligonucleotide (AS-MDM2) sensitizes androgen sensitive LNCaP cells to androgen deprivation (AD) in vitro and in vivo. In this study, we investigated the effects of AS-MDM2 combined with AD on androgen resistant LNCaP (LNCaP-Res) and moderately androgen resistant bcl-2 ove...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2763092/ https://ncbi.nlm.nih.gov/pubmed/18196567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.20731 |
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