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PKA Knockdown Enhances Cell Killing In Response To Radiation And Androgen Deprivation

The therapeutic efficacy of Gem®231, a second generation antisense molecule targeted to the RIα subunit of PKA(RIα) (AS-PKA), administered in combination with androgen deprivation (AD) and radiation therapy (RT), was examined in androgen sensitive (LNCaP) and insensitive (PC3) cell lines. Apoptosis...

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Bibliografski detalji
Glavni autori: Hensley, Harvey H., Hannoun-Levi, Jean-Michel, Hachem, Paul, Mu, Zhaomei, Stoyanova, Radka, Khor, Li-Yan, Agrawal, Sudhir, Pollack, Alan
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391603/
https://ncbi.nlm.nih.gov/pubmed/20960462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25634
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