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Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
Replication fork reversal protects forks from breakage after poisoning of Topoisomerase 1. We here investigated fork progression and chromosomal breakage in human cells in response to a panel of sublethal genotoxic treatments, using other topoisomerase poisons, DNA synthesis inhibitors, interstrand...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347635/ https://ncbi.nlm.nih.gov/pubmed/25733714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406099 |
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