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Non-enzymatic roles of human RAD51 at stalled replication forks

The central recombination enzyme RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, we use a separation-of-function allele of RAD51 that retains DNA binding, but not D-loop activity, to reveal mechanistic aspects of RAD51’s roles in the resp...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Mason, Jennifer M., Chan, Yuen-Ling, Weichselbaum, Ralph W., Bishop, Douglas K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764946/
https://ncbi.nlm.nih.gov/pubmed/31562309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12297-0
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