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Non-enzymatic roles of human RAD51 at stalled replication forks

The central recombination enzyme RAD51 has been implicated in replication fork processing and restart in response to replication stress. Here, we use a separation-of-function allele of RAD51 that retains DNA binding, but not D-loop activity, to reveal mechanistic aspects of RAD51’s roles in the resp...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Mason, Jennifer M., Chan, Yuen-Ling, Weichselbaum, Ralph W., Bishop, Douglas K.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764946/
https://ncbi.nlm.nih.gov/pubmed/31562309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12297-0
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