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Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells
Replication fork reversal protects forks from breakage after poisoning of Topoisomerase 1. We here investigated fork progression and chromosomal breakage in human cells in response to a panel of sublethal genotoxic treatments, using other topoisomerase poisons, DNA synthesis inhibitors, interstrand...
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| 出版年: | J Cell Biol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347635/ https://ncbi.nlm.nih.gov/pubmed/25733714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406099 |
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