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Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

Replication fork reversal protects forks from breakage after poisoning of Topoisomerase 1. We here investigated fork progression and chromosomal breakage in human cells in response to a panel of sublethal genotoxic treatments, using other topoisomerase poisons, DNA synthesis inhibitors, interstrand...

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Detaylı Bibliyografya
Yayımlandı:J Cell Biol
Asıl Yazarlar: Zellweger, Ralph, Dalcher, Damian, Mutreja, Karun, Berti, Matteo, Schmid, Jonas A., Herrador, Raquel, Vindigni, Alessandro, Lopes, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347635/
https://ncbi.nlm.nih.gov/pubmed/25733714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201406099
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