Uncoupling the Roles of HLA-DRB1 and HLA-DRB5 Genes in Multiple Sclerosis()

Genetic susceptibility to multiple sclerosis (MS) is associated with the MHC located on chromosome 6p21. This signal maps primarily to a 1-Mb region encompassing the HLA class II loci, and it segregates often with the HLA-DQB1*0602, -DQA1*0102, -DRB1*1501, -DRB5*0101 haplotype. However, the identifi...

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Publicat a:J Immunol
Autors principals: Caillier, Stacy J., Briggs, Farren, Cree, Bruce A. C., Baranzini, Sergio E., Fernandez-Viña, Marcelo, Ramsay, Patricia P., Khan, Omar, Royal, Walter, Hauser, Stephen L., Barcellos, Lisa F., Oksenberg, Jorge R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346327/
https://ncbi.nlm.nih.gov/pubmed/18832704
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