Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis

IMPORTANCE: Although multiple HLA alleles associated with multiple sclerosis (MS) risk have been identified, genotype-phenotype studies in the HLA region remain scarce and inconclusive. OBJECTIVES: To investigate whether MS risk-associated HLA alleles also affect disease phenotypes. DESIGN, SETTING,...

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Udgivet i:JAMA Neurol
Main Authors: Isobe, Noriko, Keshavan, Anisha, Gourraud, Pierre-Antoine, Zhu, Alyssa H., Datta, Esha, Schlaeger, Regina, Caillier, Stacy J., Santaniello, Adam, Lizée, Antoine, Himmelstein, Daniel S., Baranzini, Sergio E., Hollenbach, Jill, Cree, Bruce A. C., Hauser, Stephen L., Oksenberg, Jorge R., Henry, Roland G.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081075/
https://ncbi.nlm.nih.gov/pubmed/27244296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.0980
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