Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis

IMPORTANCE: Although multiple HLA alleles associated with multiple sclerosis (MS) risk have been identified, genotype-phenotype studies in the HLA region remain scarce and inconclusive. OBJECTIVES: To investigate whether MS risk-associated HLA alleles also affect disease phenotypes. DESIGN, SETTING,...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Isobe, Noriko, Keshavan, Anisha, Gourraud, Pierre-Antoine, Zhu, Alyssa H., Datta, Esha, Schlaeger, Regina, Caillier, Stacy J., Santaniello, Adam, Lizée, Antoine, Himmelstein, Daniel S., Baranzini, Sergio E., Hollenbach, Jill, Cree, Bruce A. C., Hauser, Stephen L., Oksenberg, Jorge R., Henry, Roland G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081075/
https://ncbi.nlm.nih.gov/pubmed/27244296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.0980
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