Association of HLA Genetic Risk Burden With Disease Phenotypes in Multiple Sclerosis

IMPORTANCE: Although multiple HLA alleles associated with multiple sclerosis (MS) risk have been identified, genotype-phenotype studies in the HLA region remain scarce and inconclusive. OBJECTIVES: To investigate whether MS risk-associated HLA alleles also affect disease phenotypes. DESIGN, SETTING,...

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Détails bibliographiques
Publié dans:JAMA Neurol
Auteurs principaux: Isobe, Noriko, Keshavan, Anisha, Gourraud, Pierre-Antoine, Zhu, Alyssa H., Datta, Esha, Schlaeger, Regina, Caillier, Stacy J., Santaniello, Adam, Lizée, Antoine, Himmelstein, Daniel S., Baranzini, Sergio E., Hollenbach, Jill, Cree, Bruce A. C., Hauser, Stephen L., Oksenberg, Jorge R., Henry, Roland G.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081075/
https://ncbi.nlm.nih.gov/pubmed/27244296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2016.0980
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