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Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial, and biomedical fields, their response to human cells has not been fully elucidated. Overall, little is known about the toxicological effects of SiNPs on the cardiovascular system. In this study, SiNPs with...

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Podrobná bibliografie
Vydáno v:Int J Nanomedicine
Hlavní autoři: Guo, Caixia, Xia, Yinye, Niu, Piye, Jiang, Lizhen, Duan, Junchao, Yu, Yang, Zhou, Xianqing, Li, Yanbo, Sun, Zhiwei
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345992/
https://ncbi.nlm.nih.gov/pubmed/25759575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S76114
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