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Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial, and biomedical fields, their response to human cells has not been fully elucidated. Overall, little is known about the toxicological effects of SiNPs on the cardiovascular system. In this study, SiNPs with...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Guo, Caixia, Xia, Yinye, Niu, Piye, Jiang, Lizhen, Duan, Junchao, Yu, Yang, Zhou, Xianqing, Li, Yanbo, Sun, Zhiwei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345992/
https://ncbi.nlm.nih.gov/pubmed/25759575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S76114
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