Silica nanoparticles induce oxidative stress, inflammation, and endothelial dysfunction in vitro via activation of the MAPK/Nrf2 pathway and nuclear factor-κB signaling

Despite the widespread application of silica nanoparticles (SiNPs) in industrial, commercial, and biomedical fields, their response to human cells has not been fully elucidated. Overall, little is known about the toxicological effects of SiNPs on the cardiovascular system. In this study, SiNPs with...

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Bibliographic Details
Published in:Int J Nanomedicine
Main Authors: Guo, Caixia, Xia, Yinye, Niu, Piye, Jiang, Lizhen, Duan, Junchao, Yu, Yang, Zhou, Xianqing, Li, Yanbo, Sun, Zhiwei
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345992/
https://ncbi.nlm.nih.gov/pubmed/25759575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S76114
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