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Characterization of LGR5 stem cells in colorectal adenomas and carcinomas

LGR5 is known to be a stem cell marker in the murine small intestine and colon, however the localization of LGR5 in human adenoma samples has not been examined in detail, and previous studies have been limited by the lack of specific antibodies. Here we used in situ hybridization to specifically exa...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Baker, Ann-Marie, Graham, Trevor A., Elia, George, Wright, Nicholas A., Rodriguez-Justo, Manuel
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345329/
https://ncbi.nlm.nih.gov/pubmed/25728748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08654
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