Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution

The genetic and morphological development of colorectal cancer is a paradigm for tumorigenesis. However, the dynamics of clonal evolution underpinning carcinogenesis remain poorly understood. Here we identify multipotential stem cells within human colorectal adenomas and use methylation patterns of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Humphries, Adam, Cereser, Biancastella, Gay, Laura J., Miller, Daniel S. J., Das, Bibek, Gutteridge, Alice, Elia, George, Nye, Emma, Jeffery, Rosemary, Poulsom, Richard, Novelli, Marco R., Rodriguez-Justo, Manuel, McDonald, Stuart A. C., Wright, Nicholas A., Graham, Trevor A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704042/
https://ncbi.nlm.nih.gov/pubmed/23766371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220353110
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados