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Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo

While the aggregate differentiation of the hematopoietic stem cell (HSC) population has been extensively studied, little is known about the lineage commitment process of individual HSC clones. Here, we provide lineage commitment maps of HSC clones under homeostasis and after perturbations of the end...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lu, Rong, Czechowicz, Agnieszka, Seita, Jun, Jiang, Du, Weissman, Irving L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347684/
https://ncbi.nlm.nih.gov/pubmed/30622181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801480116
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