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Clonal-level lineage commitment pathways of hematopoietic stem cells in vivo

While the aggregate differentiation of the hematopoietic stem cell (HSC) population has been extensively studied, little is known about the lineage commitment process of individual HSC clones. Here, we provide lineage commitment maps of HSC clones under homeostasis and after perturbations of the end...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Lu, Rong, Czechowicz, Agnieszka, Seita, Jun, Jiang, Du, Weissman, Irving L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347684/
https://ncbi.nlm.nih.gov/pubmed/30622181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1801480116
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