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Characterization of LGR5 stem cells in colorectal adenomas and carcinomas

LGR5 is known to be a stem cell marker in the murine small intestine and colon, however the localization of LGR5 in human adenoma samples has not been examined in detail, and previous studies have been limited by the lack of specific antibodies. Here we used in situ hybridization to specifically exa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Baker, Ann-Marie, Graham, Trevor A., Elia, George, Wright, Nicholas A., Rodriguez-Justo, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345329/
https://ncbi.nlm.nih.gov/pubmed/25728748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08654
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