Hyperpolarized (13)C NMR detects rapid drug-induced changes in cardiac metabolism

PURPOSE: The diseased myocardium lacks metabolic flexibility and responds to stimuli differently compared to healthy hearts. Here, we report the use of hyperpolarized (13)C NMR spectroscopy to detect sudden changes in cardiac metabolism in isolated, perfused rat hearts in response to adrenergic stim...

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Pubblicato in:Magn Reson Med
Autori principali: Khemtong, Chalermchai, Carpenter, Nicholas R., Lumata, Lloyd L., Merritt, Matthew E., Moreno, Karlos X., Kovacs, Zoltan, Malloy, Craig R., Sherry, A. Dean
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344937/
https://ncbi.nlm.nih.gov/pubmed/25168480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25419
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