Hyperpolarized (13)C NMR detects rapid drug-induced changes in cardiac metabolism

PURPOSE: The diseased myocardium lacks metabolic flexibility and responds to stimuli differently compared to healthy hearts. Here, we report the use of hyperpolarized (13)C NMR spectroscopy to detect sudden changes in cardiac metabolism in isolated, perfused rat hearts in response to adrenergic stim...

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Publicado en:Magn Reson Med
Main Authors: Khemtong, Chalermchai, Carpenter, Nicholas R., Lumata, Lloyd L., Merritt, Matthew E., Moreno, Karlos X., Kovacs, Zoltan, Malloy, Craig R., Sherry, A. Dean
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344937/
https://ncbi.nlm.nih.gov/pubmed/25168480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25419
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