Hyperpolarized (13)C NMR detects rapid drug-induced changes in cardiac metabolism

PURPOSE: The diseased myocardium lacks metabolic flexibility and responds to stimuli differently compared to healthy hearts. Here, we report the use of hyperpolarized (13)C NMR spectroscopy to detect sudden changes in cardiac metabolism in isolated, perfused rat hearts in response to adrenergic stim...

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Gepubliceerd in:Magn Reson Med
Hoofdauteurs: Khemtong, Chalermchai, Carpenter, Nicholas R., Lumata, Lloyd L., Merritt, Matthew E., Moreno, Karlos X., Kovacs, Zoltan, Malloy, Craig R., Sherry, A. Dean
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344937/
https://ncbi.nlm.nih.gov/pubmed/25168480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.25419
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