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Hyperpolarized (15)N-pyridine Derivatives as pH-Sensitive MRI Agents

Highly sensitive MR imaging agents that can accurately and rapidly monitor changes in pH would have diagnostic and prognostic value for many diseases. Here, we report an investigation of hyperpolarized (15)N-pyridine derivatives as ultrasensitive pH-sensitive imaging probes. These molecules are easi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jiang, Weina, Lumata, Lloyd, Chen, Wei, Zhang, Shanrong, Kovacs, Zoltan, Sherry, A. Dean, Khemtong, Chalermchai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360734/
https://ncbi.nlm.nih.gov/pubmed/25774436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09104
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