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Early activation of microglia and astrocytes in mouse models of Spinocerebellar Ataxia Type 1

Spinocerebellar Ataxia Type 1 (SCA1) is an incurable, dominantly inherited neurodegenerative disease of the cerebellum caused by a polyglutamine-repeat expansion in the protein ATXN1. While analysis of human autopsy material indicates significant glial pathology in SCA1, previous research has focuse...

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Vydáno v:Neuroscience
Hlavní autoři: Cvetanovic, Marija, Ingram, Melissa, Orr, Harry, Opal, Puneet
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344857/
https://ncbi.nlm.nih.gov/pubmed/25595967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.01.003
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