Aminopyridines Correct Early Dysfunction and Delay Neurodegeneration in a Mouse Model of Spinocerebellar Ataxia Type 1

The contribution of neuronal dysfunction to neurodegeneration is studied in a mouse model of spinocerebellar ataxia type 1 (SCA1) displaying impaired motor performance ahead of loss or atrophy of cerebellar Purkinje cells. Presymptomatic SCA1 mice show a reduction in the firing rate of Purkinje cell...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hourez, Raphael, Servais, Laurent, Orduz, David, Gall, David, Millard, Isabelle, de Kerchove d'Exaerde, Alban, Cheron, Guy, Orr, Harry T., Pandolfo, Massimo, Schiffmann, Serge N.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6623197/
https://ncbi.nlm.nih.gov/pubmed/21849540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0905-11.2011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados