Ribosome Excursions during mRNA Translocation Mediate Broad Branching of Frameshift Pathways

Programmed ribosomal frameshifting produces alternative proteins from a single transcript. -1-frameshifting occurs on Escherichia coli’s dnaX mRNA containing a slippery sequence AAAAAAG and peripheral mRNA structural barriers. Here we reveal hidden aspects of the frameshifting process, including its...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Yan, Shannon, Wen, Jin-Der, Bustamante, Carlos, Tinoco, Ignacio
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344849/
https://ncbi.nlm.nih.gov/pubmed/25703095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.003
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