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A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation
Ribosomal frameshifting occurs when a ribosome slips a few nucleotides on an mRNA and generates a new sequence of amino acids. Programmed −1 ribosomal frameshifting (−1PRF) is used in various systems to express two or more proteins from a single mRNA at precisely regulated levels. We used single-mol...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992627/ https://ncbi.nlm.nih.gov/pubmed/24706807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403457111 |
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