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A frameshifting stimulatory stem loop destabilizes the hybrid state and impedes ribosomal translocation

Ribosomal frameshifting occurs when a ribosome slips a few nucleotides on an mRNA and generates a new sequence of amino acids. Programmed −1 ribosomal frameshifting (−1PRF) is used in various systems to express two or more proteins from a single mRNA at precisely regulated levels. We used single-mol...

詳細記述

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書誌詳細
主要な著者: Kim, Hee-Kyung, Liu, Fei, Fei, Jingyi, Bustamante, Carlos, Gonzalez, Ruben L., Tinoco, Ignacio
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992627/
https://ncbi.nlm.nih.gov/pubmed/24706807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403457111
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