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Programmed –1 Frameshifting by Kinetic Partitioning during Impeded Translocation

Programmed –1 ribosomal frameshifting (−1PRF) is an mRNA recoding event utilized by cells to enhance the information content of the genome and to regulate gene expression. The mechanism of –1PRF and its timing during translation elongation are unclear. Here, we identified the steps that govern –1PRF...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Caliskan, Neva, Katunin, Vladimir I., Belardinelli, Riccardo, Peske, Frank, Rodnina, Marina V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112342/
https://ncbi.nlm.nih.gov/pubmed/24949973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.041
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