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Programmed −1 ribosomal frameshifting from the perspective of the conformational dynamics of mRNA and ribosomes

Programmed −1 ribosomal frameshifting (−1 PRF) is a translation mechanism that regulates the relative expression level of two proteins encoded on the same messenger RNA (mRNA). This regulation is commonly used by viruses such as coronaviruses and retroviruses but rarely by host human cells, and for...

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Библиографические подробности
Опубликовано в: :Comput Struct Biotechnol J
Главные авторы: Chang, Kai-Chun, Wen, Jin-Der
Формат: Artigo
Язык:Inglês
Опубликовано: Research Network of Computational and Structural Biotechnology 2021
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246090/
https://ncbi.nlm.nih.gov/pubmed/34257837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.06.015
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