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Programmed −1 ribosomal frameshifting from the perspective of the conformational dynamics of mRNA and ribosomes

Programmed −1 ribosomal frameshifting (−1 PRF) is a translation mechanism that regulates the relative expression level of two proteins encoded on the same messenger RNA (mRNA). This regulation is commonly used by viruses such as coronaviruses and retroviruses but rarely by host human cells, and for...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Chang, Kai-Chun, Wen, Jin-Der
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8246090/
https://ncbi.nlm.nih.gov/pubmed/34257837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.06.015
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