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Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine

A series of carbocyclic analogues of naturally-occurring marine sphingolipid pachastrissamine were prepared and biologically evaluated. The analogues were efficiently synthesized via a tandem enyne/diene-ene metathesis reaction as a key step. We found that the analogue 4b exhibited comparable cytoto...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mar Drugs
Prif Awduron: Kwon, Yongseok, Song, Jayoung, Bae, Hoon, Kim, Woo-Jung, Lee, Joo-Youn, Han, Geun-Hee, Lee, Sang Kook, Kim, Sanghee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344604/
https://ncbi.nlm.nih.gov/pubmed/25654428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13020824
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