Carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase: Biological activities and selective toxicities

Toxoplasma gondii adenosine kinase (EC.2.7.1.20) is the major route of adenosine metabolism in this parasite. The enzyme is significantly more active than any other enzyme of the purine salvage in T. gondii and has been established as a potential chemotherapeutic target for the treatment of toxoplas...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Al Safarjalani, Omar N., Rais, Reem H., Kim, Young Ah, Chu, Chung K., Naguib, Fardos N. M., el Kouni, Mahmoud H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923275/
https://ncbi.nlm.nih.gov/pubmed/20541538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2010.06.001
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