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Synthesis and Biological Evaluation of Carbocyclic Analogues of Pachastrissamine
A series of carbocyclic analogues of naturally-occurring marine sphingolipid pachastrissamine were prepared and biologically evaluated. The analogues were efficiently synthesized via a tandem enyne/diene-ene metathesis reaction as a key step. We found that the analogue 4b exhibited comparable cytoto...
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| Publicado en: | Mar Drugs |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344604/ https://ncbi.nlm.nih.gov/pubmed/25654428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13020824 |
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