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How do site-specific DNA-binding proteins find their targets?

Essentially all the biological functions of DNA depend on site-specific DNA-binding proteins finding their targets, and therefore ‘searching’ through megabases of non-target DNA. In this article, we review current understanding of how this sequence searching is done. We review how simple diffusion t...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Halford, Stephen E., Marko, John F.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434431/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15178741/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh624
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