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How do site-specific DNA-binding proteins find their targets?

Essentially all the biological functions of DNA depend on site-specific DNA-binding proteins finding their targets, and therefore ‘searching’ through megabases of non-target DNA. In this article, we review current understanding of how this sequence searching is done. We review how simple diffusion t...

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Detalhes bibliográficos
Main Authors: Halford, Stephen E., Marko, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC434431/
https://ncbi.nlm.nih.gov/pubmed/15178741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh624
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