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Protein motion from non-specific to specific DNA by three-dimensional routes aided by supercoiling
DNA-binding proteins are generally thought to locate their target sites by first associating with the DNA at random and then translocating to the specific site by one-dimensional (1D) diffusion along the DNA. We report here that non-specific DNA conveys proteins to their target sites just as well wh...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151056/ https://ncbi.nlm.nih.gov/pubmed/12628933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg125 |
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