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How do site-specific DNA-binding proteins find their targets?
Essentially all the biological functions of DNA depend on site-specific DNA-binding proteins finding their targets, and therefore ‘searching’ through megabases of non-target DNA. In this article, we review current understanding of how this sequence searching is done. We review how simple diffusion t...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC434431/ https://ncbi.nlm.nih.gov/pubmed/15178741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh624 |
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