How do site-specific DNA-binding proteins find their targets?
Essentially all the biological functions of DNA depend on site-specific DNA-binding proteins finding their targets, and therefore ‘searching’ through megabases of non-target DNA. In this article, we review current understanding of how this sequence searching is done. We review how simple diffusion t...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2004
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434431/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15178741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh624 |
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