Targeted Delivery of Antisense Oligodeoxynucleotide by Transferrin Conjugated pH-Sensitive Lipopolyplex Nanoparticles: A Novel Oligonucleotide –Based Therapeutic Strategy in Acute Myeloid Leukemia

Therapeutic use of oligodeoxynucleotides (ODNs) that hybridize to and downregulate target messenger RNAs (mRNAs) encoding proteins that contribute to malignant transformation has a sound rationale, but has had an overall limited clinical success in cancer due to insufficient intracellular delivery....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Mol Pharm
मुख्य लेखकों: Jin, Yan, Liu, Shujun, Yu, Bo, Golan, Sharon, Koh, Chee-Guan, Yang, Jintao, Huynh, Lenguyen, Yang, Xiaojuan, Pang, Jiuxia, Muthusamy, Natarajan, Chan, Kenneth K., Byrd, John C., Talmon, Yeshayahu, Lee, L. James, Lee, Robert J., Marcucci, Guido
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342499/
https://ncbi.nlm.nih.gov/pubmed/19852511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900205r
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