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A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

Limited success of antisense oligonucleotides (ASO) in clinical anticancer therapy calls for more effective delivery carriers. The goal of this study was to develop a nanoparticle system for delivery of ASO G3139, which targets mRNA of antiapoptotic protein Bcl-2, to acute myeloid leukemia (AML) cel...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Yuan, Yiming, Zhang, Lijing, Cao, Hua, Yang, Yi, Zheng, Yu, Yang, Xiao-juan
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807046/
https://ncbi.nlm.nih.gov/pubmed/27034925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1287128
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