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A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

Limited success of antisense oligonucleotides (ASO) in clinical anticancer therapy calls for more effective delivery carriers. The goal of this study was to develop a nanoparticle system for delivery of ASO G3139, which targets mRNA of antiapoptotic protein Bcl-2, to acute myeloid leukemia (AML) cel...

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Bibliografski detalji
Izdano u:Biomed Res Int
Glavni autori: Yuan, Yiming, Zhang, Lijing, Cao, Hua, Yang, Yi, Zheng, Yu, Yang, Xiao-juan
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807046/
https://ncbi.nlm.nih.gov/pubmed/27034925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1287128
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