A Polyethylenimine-Containing and Transferrin-Conjugated Lipid Nanoparticle System for Antisense Oligonucleotide Delivery to AML

Limited success of antisense oligonucleotides (ASO) in clinical anticancer therapy calls for more effective delivery carriers. The goal of this study was to develop a nanoparticle system for delivery of ASO G3139, which targets mRNA of antiapoptotic protein Bcl-2, to acute myeloid leukemia (AML) cel...

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Publicat a:Biomed Res Int
Autors principals: Yuan, Yiming, Zhang, Lijing, Cao, Hua, Yang, Yi, Zheng, Yu, Yang, Xiao-juan
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807046/
https://ncbi.nlm.nih.gov/pubmed/27034925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1287128
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