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Delivery of antisense oligonucleotide using polyethylenimine-based lipid nanoparticle modified with cell penetrating peptide

Efficient and stable delivery system of antisense oligonucleotide (ASO) is important and urgently needed. Here, an ASO delivery system, Lp-PPRP, which contains a cationic polymer based on PEI (branched, 25 kDa), named PEI-PC and a palmitic acid modified R8 (R8-PA) was prepared to deliver a kind of A...

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Detalhes bibliográficos
Publicado no:Drug Deliv
Main Authors: Yang, Shuang, Wang, Dandan, Sun, Yaojun, Zheng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6764372/
https://ncbi.nlm.nih.gov/pubmed/31544540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2019.1667453
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