Učitavanje...
Perfluoroaryl Bicyclic Cell-Penetrating Peptides for Delivery of Antisense Oligonucleotides
Exon-skipping antisense oligonucleotides are effective treatments for genetic diseases, yet exon-skipping activity requires that these macromolecules reach the nucleus. While cell-penetrating peptides can improve delivery, proteolytic instability often limits efficacy. We hypothesized that bicycliza...
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| Izdano u: | Angew Chem Int Ed Engl |
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| Glavni autori: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6248909/ https://ncbi.nlm.nih.gov/pubmed/29479836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201801167 |
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