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Synthesis and Biological Evaluation of the [d-MeAla(11)]-Epimer of Coibamide A
Coibamide A is a highly potent antiproliferative cyclic depsipeptide, which was originally isolated from a Panamanian marine cyanobacterium. In this study, the synthesis of coibamide A has been investigated using Fmoc-based solid-phase peptide synthesis followed by the cleavage of the resulting line...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342349/ https://ncbi.nlm.nih.gov/pubmed/25488840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2014.11.044 |
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