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ATG5 Promotes Death Signaling in Response to the Cyclic Depsipeptides Coibamide A and Apratoxin A

Our understanding of autophagy and lysosomal function has been greatly enhanced by the discovery of natural product structures that can serve as chemical probes to reveal new patterns of signal transduction in cells. Coibamide A is a cytotoxic marine natural product that induces mTOR-independent aut...

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Hlavní autoři: Xuemei Wan, Jeffrey D. Serrill, Ian R. Humphreys, Michelle Tan, Kerry L. McPhail, Ian G. Ganley, Jane E. Ishmael
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2018-03-01
Edice:Marine Drugs
Témata:
BiP
On-line přístup:http://www.mdpi.com/1660-3397/16/3/77
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