ATM-Mediated Stabilization of hMutL DNA Mismatch Repair Proteins Augments p53 Activation during DNA Damage

Human DNA mismatch repair (MMR) proteins correct DNA errors and regulate cellular response to DNA damage by signaling apoptosis. Mutations of MMR genes result in genomic instability and cancer development. Nonetheless, how MMR proteins are regulated has not yet been determined. While hMLH1, hPMS2, a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Luo, Yuhong, Lin, Fang-Tsyr, Lin, Weei-Chin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2004
Pynciau:
DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434232/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15226443/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.14.6430-6444.2004
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