Sensitivity of NS3 Serine Proteases from Hepatitis C Virus Genotypes 2 and 3 to the Inhibitor BILN 2061

Hepatitis C virus (HCV) displays a high degree of genetic variability. Six genotypes and more than 50 subtypes have been identified to date. In this report, kinetic profiles were determined for NS3 proteases of genotypes 1a, 1b, 2ac, 2b, and 3a, revealing no major differences in activity. In vitro s...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Thibeault, Diane, Bousquet, Christiane, Gingras, Rock, Lagacé, Lisette, Maurice, Roger, White, Peter W., Lamarre, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434094/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15220408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.14.7352-7359.2004
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