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Genetic Screen for Monitoring Hepatitis C Virus NS3 Serine Protease Activity

We have developed a genetic system to monitor the activity of the hepatitis C virus (HCV) NS3 serine protease. This genetic system is based on the bacteriophage lambda regulatory circuit where the viral repressor cI is specifically cleaved to initiate the switch from lysogeny to lytic infection. An...

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Autors principals: Martinez, Miguel Angel, Clotet, Bonaventura
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153332/
https://ncbi.nlm.nih.gov/pubmed/12709356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1760-1765.2003
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