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Genetic Screen for Monitoring Hepatitis C Virus NS3 Serine Protease Activity

We have developed a genetic system to monitor the activity of the hepatitis C virus (HCV) NS3 serine protease. This genetic system is based on the bacteriophage lambda regulatory circuit where the viral repressor cI is specifically cleaved to initiate the switch from lysogeny to lytic infection. An...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Martinez, Miguel Angel, Clotet, Bonaventura
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12709356/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.5.1760-1765.2003
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