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Genetic Screen for Monitoring Hepatitis C Virus NS3 Serine Protease Activity

We have developed a genetic system to monitor the activity of the hepatitis C virus (HCV) NS3 serine protease. This genetic system is based on the bacteriophage lambda regulatory circuit where the viral repressor cI is specifically cleaved to initiate the switch from lysogeny to lytic infection. An...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Martinez, Miguel Angel, Clotet, Bonaventura
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2003
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12709356/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.5.1760-1765.2003
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