Sensitivity of NS3 Serine Proteases from Hepatitis C Virus Genotypes 2 and 3 to the Inhibitor BILN 2061

Hepatitis C virus (HCV) displays a high degree of genetic variability. Six genotypes and more than 50 subtypes have been identified to date. In this report, kinetic profiles were determined for NS3 proteases of genotypes 1a, 1b, 2ac, 2b, and 3a, revealing no major differences in activity. In vitro s...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thibeault, Diane, Bousquet, Christiane, Gingras, Rock, Lagacé, Lisette, Maurice, Roger, White, Peter W., Lamarre, Daniel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2004
Gaiak:
Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC434094/
https://ncbi.nlm.nih.gov/pubmed/15220408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.14.7352-7359.2004
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